Neural Mechanisms Determining the Capacity on Working Memory Tasks
Working memory is the ability to temporarily retain §goal-relevant visuospatial information in memory. §This ability is crucial for higher cognitive §function and its deficits can be found in disorders §such as ADHD. Fortunately, working memory can be §trained. In this thesis, Fredrik Edin combines §experimental techniques such as functional MR §imaging with mathematical modeling to investigate §the neural basis of the capacity of working memory. §He finds neural connections between and within §working memory-related brain regions that increase §the capacity of or access to working memory, and he §develops a simple mathematical equation for working §memory capacity. His research may further help §explain the link between distractibility and low §working memory capacity found in ADHD. A specific §aim of this thesis has been to describe the §mechanistic model in a way that is accessible to §people without a modeling background.